Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : EKOLOGIA : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup

PERBANDINGAN POTENSI ANALGETIK EKSTRAK ETANOL DAN AIR UMBI RUMPUT TEKI (Cyperus rotundus L.) TERHADAP TIKUS Sprague Dawley Erni Rustiani; Min Rahminiwati; Tia Mutiara
EKOLOGIA Vol 17, No 2 (2017): JURNAL ILMIAH ILMU DASAR DAN LINGKUNGAN HIDUP
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.736 KB) | DOI: 10.33751/ekol.v17i2.762

Abstract

The aim of this study is to compare the potential of ethanolic and water extracted of teki grasstuber on white male rat strain Sprague Dawley at two months of age and 200 g of body weight. The rats were divided among four groups. Each group consists of six rats. The groupswere ethanolic and water extracted of teki grass tuber, positive control group (Paracetamol) and a negative control group (distilled water). Analgesic potency was tested by inducing pain stimuli previously to the animals, in the form of heat stimuli by putting it ona hot plate with the temperature of 55C. The responses of rats observed were licking and moving or lifting of their legs. Observations were made for 1 minute, before and after administration of pain stimulus at 15, 30, 45 and 60 minute. The results showed that ethanol and water extract at an effective dose of 49 mg / 200 g of BW, gave relatively the same effect as an analgesic or positive control group.Keywords : analgesic, ethanol and water extract of teki grass tuber, pain
PERBANDINGAN POTENSI ANALGETIK EKSTRAK ETANOL DAN AIR UMBI RUMPUT TEKI (Cyperus rotundus L.) TERHADAP TIKUS Sprague Dawley Erni Rustiani; Min Rahminiwati; Tia Mutiara
Ekologia: Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup Vol 17, No 2 (2017): Ekologia : Jurnal Ilmiah Ilmu Dasar dan Lingkungan Hidup
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/ekol.v17i2.762

Abstract

The aim of this study is to compare the potential of ethanolic and water extracted of teki grasstuber on   white  male  rat strain Sprague  Dawley  at  two  months of age and ± 200 g of body weight. The rats were divided among four groups. Each group consists of six rats. The  groupswere ethanolic and water extracted  of  teki  grass tuber, positive control group (Paracetamol) and a negative control group (distilled water). Analgesic potency was tested by inducing pain stimuli previously to the animals, in the form of  heat stimuli  by putting it ona hot plate with  the temperature of 55°C. The responses of rats observed were licking and moving or lifting of their legs. Observations  were made for 1 minute, before  and  after  administration  of  pain stimulus at 15, 30, 45  and 60 minute. The results showed that ethanol and  water  extract  at an effective dose of 49 mg / 200 g of BW, gave relatively the same effect as an analgesic or   positive control group. Keywords : analgesic, ethanol and water extract of teki grass tuber, pain